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Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling

✍ Scribed by Godowski, Paul J.; Yang, Ruey-Bing; Mark, Melanie R.; Gray, Alane; Huang, Arthur; Xie, Ming Hong; Zhang, Min; Goddard, Audrey; Wood, William I.; Gurney, Austin L.

Book ID
109701894
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
338 KB
Volume
395
Category
Article
ISSN
0028-0836

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Toll-like receptor-2 mediates lipopolysa
Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling
✍ Godowski, Paul J.; Yang, Ruey-Bing; Mark, Melanie R.; Gray, Alane; Huang, Arthur πŸ“‚ Article πŸ“… 1998 πŸ› Nature Publishing Group 🌐 English βš– 338 KB

Vertebrates and invertebrates initiate a series of defence mechanisms following infection by Gram-negative bacteria by sensing the presence of lipopolysaccharide (LPS), a major component of the cell wall of the invading pathogen. In humans, monocytes and macrophages respond to LPS by inducing the ex