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Toll-like receptor 2 –196 to 174del polymorphism influences the susceptibility of Japanese people to gastric cancer

✍ Scribed by Tomomitsu Tahara; Tomiyasu Arisawa; Fangyu Wang; Tomoyuki Shibata; Masakatsu Nakamura; Mikijyu Sakata; Ichiro Hirata; Hiroshi Nakano


Book ID
108583994
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
97 KB
Volume
98
Category
Article
ISSN
1347-9032

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The toll-like receptor 2 (TLR2) -196 to
✍ Hans-Dieter Nischalke; Martin Coenen; Cordula Berger; Katharina Aldenhoff; Tobia 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 French ⚖ 306 KB

## Abstract Chronic hepatitis C virus (HCV) infection is a major risk factor for hepatocellular carcinoma (HCC). HCV proteins core and NS3 can bind to toll‐like receptor 2 (TLR2) and trigger inflammatory responses. Polymorphisms in the __TLR2__ gene predispose to various forms of malignancy but hav