Tolerogenic dendritic cells induced by v
✍
Luciano Adorini; Giuseppe Penna; Nadia Giarratana; Milan Uskokovic
📂
Article
📅
2002
🏛
John Wiley and Sons
🌐
English
⚖ 116 KB
## Abstract Dendritic cells (DCs) not only induce but also modulate T cell activation. 1,25‐dihydroxyvitamin D~3~ [1,25(OH)~2~D~3~] induces DCs with a tolerogenic phenotype, characterized by decreased expression of CD40, CD80, and CD86 costimulatory molecules, low IL‐12 and enhanced IL‐10 secretion