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Tolerant and diverse natural killer cell repertoires in the absence of selection

✍ Scribed by Sandra Andersson; Jenny-Ann Malmberg; Karl-Johan Malmberg

Book ID
113955979
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
706 KB
Volume
316
Category
Article
ISSN
0014-4827

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Natural killer (NK) cells are lymphocytes which can kill tumor and virus-infected cells, and mediate acute rejection of bone marrow grafts. NK-cell killing is directed primarily at target cells which do not express sufficient levels of self-major histocompatibility complex (MHC) class-I molecules. I