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Tolerance to hexobarbital and supersensitivity to pilocarpine after chronic barbital treatments in the rat

✍ Scribed by Göran Wahlström; Torsten Ekwall

Book ID
118322107
Publisher
Elsevier Science
Year
1976
Tongue
English
Weight
567 KB
Volume
38
Category
Article
ISSN
0014-2999

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The interaction between electrically induced convulsions and tolerance in the abstinence period after chronic barbital treatments in the rat
✍ Göran Wahlström 📂 Article 📅 1976 🏛 Springer 🌐 English ⚖ 632 KB

The effect of electrically induced convulsions was tested on the tolerance to hexobarbital after chronic barbital treatment in male rats. In two experiments barbital was given in the drinking water for more than 20 weeks. The dose was around 200 mg/kg/day. Tolerance was tested with an EEG threshold