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Tolerance to and dependence on MK-801 (dizocilpine) in rats

✍ Scribed by William D. Wessinger

Book ID
113226198
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
741 KB
Volume
49
Category
Article
ISSN
0091-3057

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The mRNA expression pattern for four different immediate early genes was examined dynamically in rat brain after administration of phencyclidine (PCP; 0.86 or 8.6 mg/kg) or MK801 (0.1 or 1.0 mg/kg). Following each treatment, the expression of cfos, cjun, junB, and zif268 mRNA changed distinctively a