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Tolerance Induction by Acylated Peptides: Effect on Encephalitogenic T cell lines

โœ Scribed by Joanne St Louis; Xiang-Ming Zhang; Ellen Heber-Katz; Shashi Uniyal; Deborah Robbinson; Bhagirat Singh; Gill H Strejan


Book ID
115621638
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
324 KB
Volume
12
Category
Article
ISSN
0896-8411

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Encephalitogenic T cells from Lewis rats use a restricted T cell receptor (TCR) gene combination, Vbeta8.2 and Valpha2. The oral administration of myelin basic protein (MBP) to Lewis rats prior to encephalitogenic challenge results in a marked inhibition of clinical neurologic signs of encephalitis,