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Tolerance, immune regulation, and autoimmunity: cells and cytokines that make a difference

✍ Scribed by Roberta Pelanda; Ciriaco A Piccirillo


Book ID
108099615
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
113 KB
Volume
20
Category
Article
ISSN
0952-7915

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ollowing antigen exposure, mature lymphocytes require intense, prolonged and repeated proliferation to establish a rapid immune response and generate immunological memory. Proliferation also precedes induction of tolerance to soluble antigens. In addition, immune cells in bone marrow or thymus under