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Tolerance and selective cross-tolerance to the motivational effects of opioids

✍ Scribed by T. S. Shippenberg; M. W. Emmett-Oglesby; F. J. Ayesta; A. Herz

Publisher
Springer
Year
1988
Tongue
English
Weight
607 KB
Volume
96
Category
Article
ISSN
0033-3158

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## Abstract Prolonged iontophoretic administrations of δ‐ and μ‐selective opioid receptor agonists were conducted in the hippocampus of rats, in order to study the possible development of acute tolerance to the excitatory effects of the opioids. Acute tolerance (AT) to the excitatory effects of the