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Tolerance and cross-tolerance to theophylline-induced stimulation of locomotor activity in rats

✍ Scribed by Ira B. Finn; Stephen G. Holtzman

Book ID
118343125
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
555 KB
Volume
42
Category
Article
ISSN
0024-3205

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✍ I. B. Finn; S. G. Holtzman πŸ“‚ Article πŸ“… 1987 πŸ› Springer 🌐 English βš– 741 KB

The pharmacologic specificity of tolerance to caffeine-induced stimulation of locomotor activity was studied in adult male rats that were given access to either caffeine solution (0.5 or 1.0 mg/ml) or plain water for 10 min every 6 h on a chronic daily basis; daily caffeine intake averaged 41 and 62