Tolerance and cross-tolerance to cannabinoids in mice: schedule-controlled responding and hypothermia
โ Scribed by Harinder Singh; David R. Schulze; Lance R. McMahon
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 375 KB
- Volume
- 215
- Category
- Article
- ISSN
- 0033-3158
No coin nor oath required. For personal study only.
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Current perspectives on clinical use of N-methyl-D -aspartate (NMDA) receptor antagonists infer acute and repeated administration schedules for management of different pathological states. Development of tolerance and cross-tolerance between different antagonists may significantly affect their clini
## Introduction Previous research has shown that heavy cannabis users develop tolerance to the impairing effects of ฮ9-tetrahydrocannabinol (THC) on neurocognitive functions. Animal studies suggest that chronic cannabis consumption may also produce cross-tolerance for the impairing effects of alcoh