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Tobacco mosaic virus-enkephalin conjugates: Potentiation of opioid activity

✍ Scribed by Kriwaczek, V. Marly; Schwyzer, Robert; Gillan, Maureen G.C.; Paterson, Stewart J.; Kosterlitz, Hans W.

Book ID
122964125
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
326 KB
Volume
2
Category
Article
ISSN
0196-9781

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✍ Rudolf Wunderlin; Shub Dev Sharma; Panagiota Minakakis; Robert Schwyzer 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 German ⚖ 683 KB

## Abstract Asymmetric disulfide conjugates of mercaptosuccinyl tobacco mosaic virus (TMV ∼ SH) with __N__^α^‐desacetyl‐__N__^α^‐5‐(mercaptovaleryl)‐α‐melanotropin were prepared __via__ the __S__‐sulfoderivative of the peptide. The conjugates, TMV ∼ SS ∼ α‐MSH(__n__), contained up to __n__ = 330 d