Homozygosity for a Common Polymorphism i
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Zaidi, F.K.; Wareham, N.J.; McCarthy, M.I.; Holdstock, J.; Kalloo-Hosein, H.; Kr
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Article
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1997
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John Wiley and Sons
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English
β 81 KB
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A commonly occurring sequence variant in the islet-specific promoter of the glucokinase gene (-30 G to A) has been variably reported to be associated with reduced insulin secretory responses to oral glucose. The effect of this promoter variant may be subtle and only become apparent under conditions