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To treat or not to treat? A meta-analysis of the use of cholinesterase inhibitors in mild cognitive impairment for delaying progression to Alzheimer’s disease

✍ Scribed by Breno Satler Diniz; Jony Arrais Pinto; Maria Luiza Cavichioli Gonzaga; Fabiana Meira Guimarães; Wagner Farid Gattaz; Orestes Vicente Forlenza

Publisher: Springer-Verlag
Year: 2009
Tongue: English
Weight: 272 KB
Volume: 259
Category: Article
ISSN: 1433-8491
DOI: 10.1007/s00406-008-0864-1

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Objectives. To report on a Numbers Needed to Treat (NNT) analysis of the literature identi®ed through a systematic review of trials of cholinesterase inhibitors in Alzheimer's Disease. Design. Search of Medline (1966±1998), EMBASE (1994±1999) and Psychlit (1974±1998) using the keywords cholinestera