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TNFα mediated osteoblastic inhibition of osteoclast development is caused by a block in monocyte differentiation

✍ Scribed by E.A. Atanga⁎; S. Dolder; W. Hofstetter


Book ID
116324387
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
66 KB
Volume
48
Category
Article
ISSN
8756-3282

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## Abstract IL‐17 is a proinflammatory cytokine crucial for osteoclastic bone resorption in the presence of osteoblasts or synoviocytes in rheumatoid arthritis. However, the role of IL‐17 in osteoclastogenesis from human monocytes alone remains unclear. Here, we investigated the role of IL‐17 in os