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TNFα genotype affects TNFα release, insulin sensitivity and the severity of liver disease in HCV chronic hepatitis

✍ Scribed by Luca Valenti; Edoardo Pulixi; Anna Ludovica Fracanzani; Paola Dongiovanni; Marco Maggioni; Alessandra Orsatti; Cristina Gianni; Silvia Fargion


Book ID
116650808
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
132 KB
Volume
43
Category
Article
ISSN
0168-8278

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In patients with chronic hepatitis C, the influence of the genetic heterogeneity of the hepatitis C virus (HCV) on the progression of liver disease and on the responsiveness to interferon therapy is a matter of controversy. In this study we evaluated the genetic complexity of HCV by singlestrand con