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TNFα blockade in human diseases: An overview of efficacy and safety

✍ Scribed by Jan Lin; David Ziring; Sheetal Desai; Sungjin Kim; Maida Wong; Yael Korin; Jonathan Braun; Elaine Reed; David Gjertson; Ram Raj Singh

Book ID
113540086
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
335 KB
Volume
126
Category
Article
ISSN
1090-2341

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## Abstract ## Objective To investigate the safety of therapeutic tumor necrosis factor α (TNFα) blockade in patients with systemic lupus erythematosus (SLE), in whom this proinflammatory cytokine is significantly increased and may be involved in the disease pathogenesis. ## Methods In an open‐l