Sustained NF-kappaB activity in chronic
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Lukas P. Frenzel; Rainer Claus; Nadine Plume; Janine Schwamb; Carolin Konermann;
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Article
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2010
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John Wiley and Sons
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French
⚖ 330 KB
👁 1 views
## Abstract Inappropriate nuclear factor (NF) κB activity is one major hallmark of B‐cell malignancies and chronic lymphocytic leukemia (CLL). NFκB‐dependent genes are involved in antiapoptosis, cell proliferation and metastasis and are responsible for survival and proliferation of tumors. However,