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TNF-α regulates expression of cyclo-oxygenase-2 by fibroblasts in Crohn’s disease

✍ Scribed by D. Beddy; R. W. G. Watson; J. M. Fitzpatrick; P. R. O’Connell


Publisher
Springer-Verlag
Year
2002
Tongue
English
Weight
849 KB
Volume
171
Category
Article
ISSN
1863-4362

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## Abstract Crohn's disease (CD) and ulcerative colitis (UC) are inflammatory bowel diseases (IBD) that are characterized by chronic intestinal inflammation and a constant influx of leukocytes mediated by pro‐inflammatory cytokines and chemokines. The intestinal expression of the CXCR1‐binding chem