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TNF-α promoter, Nod2 and toll-like receptor-4 polymorphisms and the in vivo and ex vivo response to endotoxin

✍ Scribed by Emile F. Schippers; Cornelis van 't Veer; Sjaak van Voorden; Cerithsa A.E. Martina; Saskia le Cessie; Jaap T. van Dissel

Book ID: 116397401
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 173 KB
Volume: 26
Category: Article
ISSN: 1043-4666
DOI: 10.1016/j.cyto.2003.12.003

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## Abstract Heat shock protein 60 (HSP60) from __Chlamydia pneumoniae__ was described to trigger __in vitro__ inflammatory and cytokine responses including TNF and IL‐12p40. Although it can be found in atherosclerotic plaques of patients, the stimulatory potential of chlamydial and other HSP60 __in