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TNF-α-mediated cell death is attenuated by retrovirus delivery of human heme oxygenase-1 gene into human microvessel endothelial cells

✍ Scribed by T Kushida; G LiVolti; A.I Goodman; N.G Abraham

Book ID
117232697
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
307 KB
Volume
34
Category
Article
ISSN
0041-1345

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Heme oxygenase (HO) is the rate-limiting enzyme in the formation of bilirubin, an antioxidant, and carbon monoxide (CO), a cell cycle modulator and a vasodilator. Cyclooxygenase (COX) is a hemeprotein that catalyzes the conversion of arachidonic acid (AA) to various prostanoids, which play an import