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TNF-α inhibits the CD3-mediated upregulation of voltage-gated K+ channel (Kv1.3) in human T cells

✍ Scribed by Bo Pang; Haifeng Zheng; Dong Hoon Shin; Kyeong Cheon Jung; Jae Hong Ko; Ki Young Lee; Tong Mook Kang; Sung Joon Kim


Book ID
116299565
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
384 KB
Volume
391
Category
Article
ISSN
0006-291X

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## Abstract Using the whole-cell patch-clamp technique, we investigated the influence of 8-prenylnaringenin on the activity of the voltage-gated Kv1.3 potassium channels in the human leukemic T lymphocyte cell line Jurkat. 8-prenylnaringenin is a potent plant-derived phytoestrogen that has been fou