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TNF-α decreases expression of Thrombomudulin and endothelial protein C receptor in human endothelial cells

✍ Scribed by B. Nan; S. Yan; H. Chai; P. Lin; Q. Yao; C. Chen


Book ID
116701523
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
49 KB
Volume
121
Category
Article
ISSN
0022-4804

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We examined the effects of the proinflammatory cytokine, tumor necrosis factora (TNF,), on the expression of proteolytically activated thrombin receptor (PATR) in human umbilical vein endothelial cells (HUVEC). PATR mRNA and protein levels were measured in confluent HUVEC monolayers after challenge