TMBHMM: A frequency profile based HMM for predicting the topology of transmembrane beta barrel proteins and the exposure status of transmembrane residues

A sequence-based computational model for

A sequence-based computational model for the prediction of the solvent accessible surface area for α-helix and β-barrel transmembrane residues

✍ Chengqi Wang; Lili Xi; Shuyan Li; Huanxiang Liu; Xiaojun Yao 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 816 KB

## Abstract Predicting the solvent accessible surface area (ASA) of transmembrane (TM) residues is of great importance for experimental researchers to elucidate diverse physiological processes. TM residues fall into two major structural classes (α‐helix membrane protein and β‐barrel membrane protei