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TLR2 and TLR4 activation induces p38 MAPK-dependent phosphorylation of S6 kinase 1 in C2C12 myotubes

✍ Scribed by Zbinden‑Foncea, Hermann; Deldicque, Louise; Pierre, Nicolas; Francaux, Marc; Raymackers, Jean‑Marc


Book ID
119739903
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
267 KB
Volume
36
Category
Article
ISSN
1065-6995

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## Abstract Myostatin is a negative regulator of skeletal muscle mass. The pathways employed in modulating myostatin gene expression are scarcely known. We aimed to determine the signaling pathway of myostatin induction by a histone deacetylase (HDAC) inhibitor–trichostatin A (TSA) in differentiate