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TL 333, a benzhydro[g]quinoline, stimulates both D-1 and D-2 dopamine receptors: Implications for the selectivity of LY 141865 towards the D-2 receptor

✍ Scribed by Yoshiharu Itoh; Mark E. Goldman; John W. Kebabian

Book ID
115879196
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
220 KB
Volume
108
Category
Article
ISSN
0014-2999

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## Abstract In this study we examined the selectivity of dopamine (DA) for rat striatal DA D~1~ and D~2~ receptors. In a Krebs‐HEPES buffer, the K~i~ values of DA for D~1~ binding sites (labelled with [^3^H]SCH23390) and D~2~ binding sites (labelled with [^3^H]spiroperidol) in striatal membranes am