This Brief describes the calibration of titration calorimeters (ITCs) and calculation of stoichiometry, equilibrium constants, enthalpy changes, and rate constants for reactions in solution. A framework/methodology for model development for analysis of ITC data is presented together with methods for
Titration Calorimetry: From Concept to Application
โ Scribed by Hansen, Lee D.;Quinn, Colette F.;Transtrum, Mark K
- Publisher
- Springer International Publishing : Imprint: Springer
- Year
- 2018
- Tongue
- English
- Series
- SpringerBriefs in molecular science
- Category
- Library
No coin nor oath required. For personal study only.
โฆ Synopsis
This Brief describes the calibration of titration calorimeters (ITCs) and calculation of stoichiometry, equilibrium constants, enthalpy changes, and rate constants for reactions in solution. A framework/methodology for model development for analysis of ITC data is presented together with methods for assessing the uncertainties in determined parameters and test data sets. This book appeals to beginners, as well as to researchers and professionals in the field.
โฆ Subjects
Medicine;Physical organic chemistry
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Calorimetry, as a technique for thermal analysis, has a wide range of applications which are not only limited to studying the thermal characterisation (e.g. melting temperature, denaturation temperature and enthalpy change) of small and large drug molecules, but are also extended to characterisation
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