## Abstract The study was initially designed to differentiate human bone marrow–derived mesenchymal stem cells (MSC) into chondrocyte‐like cells, for use in tissue engineering. We cultured MSCs in defined chondrogenic medium as pellet cultures supplemented with transforming growth factor (TGF)‐β1 o
Tissue transglutaminase regulates chondrogenesis in mesenchymal stem cells on collagen type XI matrices
✍ Scribed by Shobana Shanmugasundaram; Sheila Logan-Mauney; Kaitlin Burgos; Maria Nurminskaya
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 435 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0939-4451
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The formation of cartilaginous tissue by chondroprogenitor cells, whether in vivo or in vitro, appears to require a critical initial stage of “condensation” in which intercellular space is reduced through an aggregation of cells, leading to development of cell‐to‐cell junctions followed
## Abstract Bone marrow mesenchymal stem cells (MSCs) are candidate cells for cartilage tissue engineering. This is due to their ability to undergo chondrogenic differentiation after extensive expansion in vitro and stimulation with various biomaterials in three‐dimensional (3‐D) systems. Collagen
## Abstract Type I collagen is the most abundant extracellular matrix protein in bone and contains arginine– glycine–aspartic acid sequences that promote cell adhesion and proliferation. We have previously shown that human mesenchymal stem cells (hMSCs) seeded in three‐dimensional (3D) collagen gel
## Abstract Recent evidence indicates that a major drawback of current cartilage‐ and disc‐tissue engineering is that human mesenchymal stem cells (MSCs) rapidly express type X collagen—a marker of chondrocyte hypertrophy associated with endochondral ossification. Some studies have attempted to use