Tissue toxicity of doxorubicin in first and second hyperthermic isolated limb perfusion—an experimental study in dogs

Hyperthermic isolated limb perfusion wit

Hyperthermic isolated limb perfusion with Cis-diamminedichloro-platinum. II. An experimental study in dogs with a balloon-occlusion technique for repeated high-dose treatment

✍ Wessalowski, R. ;Wilhelm, M. ;Torsello, S. ;Sager, M. ;Güttler, J. ;Jürgens, H. 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 464 KB

## Abstract Isolated organ perfusion is attractive for regional high‐dose chemotherapy because of its advantage to reduce whole body toxicity. Intraoperative hyperthermic isolated perfusion procedures involving a heart‐lung machine have been developed, but repeated treatments carry a high risk of v