Tissue swelling and intracellular pH in the CA1 region of anoxic rat hippocampus
β Scribed by Detlev Melzian; Eckhard Scheufler; Manfred Grieshaber; Frank Tegtmeier
- Book ID
- 107905560
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 544 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0165-0270
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π SIMILAR VOLUMES
Intracellular recordings were made from hippocampal CA1 pyramidal cells in slices where the CA3/CA4 region had been lesioned using intracerebroventricular kainic acid. In 55% of the cells studied orthodromic excitation evoked bursts of action potentials. This bursting activity was associated with a
The effects of intracellular pH (pH(i)), paramagnetic macroscopic, and microscopic susceptibility on T(1) in the rotating frame (T(1rho)) were studied in rat brain. Intracellular acidosis was induced by hypercapnia and pH(i), T(1rho), T(2), diffusion, and cerebral blood volume (CBV) were quantified.
## Abstract We have previously shown that exposing rats to a relatively high dose of ethanol during early postnatal life can result in an alteration in spatial learning ability. The hippocampal formation is known to be involved in the control of this ability. The purpose of the present study was to