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Tissue-specific knockouts of steroidogenic factor 1

✍ Scribed by Liping Zhao; Marit Bakke; Neil A Hanley; Gregor Majdic; Nancy R Stallings; Pancharatnam Jeyasuria; Keith L Parker

Book ID
116733465
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
481 KB
Volume
215
Category
Article
ISSN
0303-7207

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## Abstract Summary: The bacteriophage Cre recombinase provides a powerful approach for tissue‐specific gene inactivation. Using a Cre transgene driven by the common alpha subunit of glycoprotein hormones (Ξ±GSU‐Cre), we have previously inactivated steroidogenic factor 1 (SF‐1) in the anterior pitui