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Tissue selective drug delivery utilizing carrier-mediated transport systems

โœ Scribed by Akira Tsuji


Book ID
114163749
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
55 KB
Volume
62
Category
Article
ISSN
0168-3659

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TISSUE-SELECTIVE UPTAKE OF PRAVASTATIN I
โœ Masayo Yamazaki; Taro Tokui; Michi Ishigami; Yuichi Sugiyama ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 780 KB

Previously we demonstrated that a hydrophilic HMG-CoA reductase inhibitor, pravastatin, was actively taken up by the liver via the 'multispecific anion transporter' using isolated rat hepatocytes (M. Yamazaki, H. Suzuki, M. Hanano, T. Tokui, T. Komai, and Y. Sugiyama, Am. J. Physiol., 264, G36-G44 (