Characterization of indium-111 labeled r
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D. J. Hnatowich; F. Virzi; P. W. Doherty; J. Wilson; J. Rosa; J. E. Ansell
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Article
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1987
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Springer
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English
β 708 KB
The in vitro functional properties of recombinant tissue plasminogen activator (rt-PA), its biodistribution in mice, and its pharmacokinetics and clot localization properties in dogs have been investigated after labeling rt-PA with 111In. The rt-PA was coupled with the bicyclic anhydride of DTPA usi