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Tissue plasminogen activator (t-PA) production by human fibroblasts using a bioreactor with t-PA adsorption column

โœ Scribed by S. Mitsuda; Y. Matsuda; N. Kobayashi; A. Suzuki; Y. Itagaki; E. Kumazawa; K. Higashio; G. Kawanishi


Publisher
Springer
Year
1991
Tongue
English
Weight
311 KB
Volume
7
Category
Article
ISSN
1615-7605

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Continuous production of tissue plasmino
โœ Shinjiro Mitsuda; Yoshiaki Matsuda; Naoki Kobayashi; Akira Suzuki; Yasuharu Itag ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Springer ๐ŸŒ English โš– 883 KB

Ceramic pieces composed of 99.5% Al2O3, 3 to 6 mm long, were found to be a good matrix for growth of the human embryonic lung diploid fibroblast, IMR-90 cells. The tissue plasminogen activator (t-PA) was secreted in DME medium containing proteose peptone as a t-PA inducer. In addition, production of