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Tissue plasminogen activator (t-PA) is increased in endometrial hyperplasia, and urokinase plasminogen activator (u-PA) is increased in endometrial carcinoma

✍ Scribed by J. Nordengren; B. Gustavsson; B. Casslén


Book ID
119154492
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
125 KB
Volume
8
Category
Article
ISSN
0268-9499

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Tissue samples were obtained from normal (n ϭ 92), hyperplastic (n ϭ 22) and malignant (n ϭ 35) endometria. Urokinase and tissue plasminogen activators (u-PA, t-PA) were assayed in acetate detergent buffer extracts and their mRNAs quantitated in autoradiograms of Northern blots. The tissue content o