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Tissue-plasminogen activator, plasminogen activator inhibitor and risk of peripheral arterial disease

โœ Scribed by Felicity B Smith; Amanda J Lee; Ann Rumley; F Gerald; R Fowkes; Gordon D.O Lowe

Book ID
118324527
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
724 KB
Volume
115
Category
Article
ISSN
0021-9150

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Effect of oral defibrotide on tissue-pla
Effect of oral defibrotide on tissue-plasminogen activator and tissue-plasminogen activator inhibitor balance
โœ F. Violi; D. Ferro; M. Saliola; C. Quintarelli; S. Basili; F. Balsano ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Springer ๐ŸŒ English โš– 491 KB

Defibrotide, a polydeoxyribonucleotide of mammalian origin, has been shown to reduce the blood level of the plasminogen activator inhibitor, and so to increase the activity of tissue plasminogen activator without any adverse effect. A randomized, double-blind, placebo-controlled study has been done