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Tissue microarray technology: validation in colorectal carcinoma and analysis of p53, hMLH1, and hMSH2 immunohistochemical expression

✍ Scribed by Florence Jourdan; Nicole Sebbagh; Eva Comperat; Najat Mourra; Antoine Flahault; Sylviane Olschwang; Alex Duval; Richard Hamelin; Jean-François Flejou


Publisher
Springer
Year
2003
Tongue
English
Weight
382 KB
Volume
443
Category
Article
ISSN
1432-2307

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✍ LEAHY, DERMOT T.; SALMAN, REEM; MULCAHY, HUGH; SHEAHAN, KIERAN; O'DONOGHUE, DIAR 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 643 KB

Abnormalities in the pS3 tumour suppressor gene and in the expression of its protein are common in colorectal carcinoma. The prognostic significance of these p53 abnormalities was studied in 66 patients with colorectal cancer, followed for more than 10 years. Single-strand conformation polymorphism