Tissue localization and kinetics of pit cells or large granular lymphocytes in the liver of rats treated with biological response modifiers

Electron microscopic observations on the

Electron microscopic observations on the accumulation of large granular lymphocytes (pit cells) and kupffer cells in the liver of rats treated with continuous infusion of interleukin-2

✍ Dr. Luc Bouwens; Andreas Marinelli; Peter J. K. Kuppen; Alex M. M. Eggermont; Co 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 747 KB

Treatment schedules were investigated for in vivo induction of lymphokine-activated killer cells in the rat liver. Treatment of rats with continuous sys- temic or regional infusion of recombinant human interleukin-2 with a dose of 4 to 8 x lo4 U/day during 7 days, resulted in an increase in number o