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Tissue factor pathway inhibitor, vascular risk factors and subclinical atherosclerosis: The Multi-Ethnic Study of Atherosclerosis

✍ Scribed by C.T. Mitchell; A. Kamineni; W. Palmas; M. Cushman

Book ID: 118422566
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 304 KB
Volume: 207
Category: Article
ISSN: 0021-9150
DOI: 10.1016/j.atherosclerosis.2009.04.024

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Tissue factor (TF) initiates the extrinsic pathway of blood coagulation by acting as a cofactor for Factor VII. Inhibition of the Factor VIIa-TF complex is mediated by the tissue factor pathway inhibitor (TFPI), which is a serine protease inhibitor with three Kunitz-type domains. The localization of