Tissue engineering in cardiovascular disease: A report

• Book ID: 102292643
• Publisher: John Wiley and Sons
• Year: 1995
• Tongue: English
• Weight: 219 KB
• Volume: 29
• Category: Article
• ISSN: 0021-9304
• DOI: 10.1002/jbm.820291202

✦ Synopsis

Tissue engineering is an emerging discipline that applies engineering principles to create devices for the study, restoration, modification, and assembly of functional tissues and organs from native or synthetic sources. In the cardiovascular field, tissue engineering is being applied to the development of autograft heart valves by in situ autologous cell repopulation of decellularized homograft or xenograft heart valves or the de nozm construction of heart valve leaflets from degradable polymer scaffolds and the patient's own cells. In addition, vascular grafts are being assembled from autologous endothelial cells, smooth muscle cells, and fibroblasts using tissue engineering principles. Other applications of tissue engineering include the development of bioartificial skin, cartilage, and bone, and the encapsulation of cells for the treatment of pain, diabetes. Parkinson's disease, and Alzheimer's disease.