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Tissue distribution and function of the Aryl hydrocarbon receptor repressor (AhRR) in C57BL/6 and Aryl hydrocarbon receptor deficient mice

✍ Scribed by Thorsten Bernshausen; Bettina Jux; Charlotte Esser; Josef Abel; Ellen Fritsche

Publisher: Springer-Verlag
Year: 2005
Tongue: English
Weight: 242 KB
Volume: 80
Category: Article
ISSN: 0340-5761
DOI: 10.1007/s00204-005-0025-5

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## Abstract The aryl hydrocarbon receptor (AhR) is a receptor/transcription factor which regulates cytochrome P450 (__CYP__) gene transcription and which is activated by environmental carcinogens, some of which are associated with increased breast cancer risk. Here, we show that the AhR is over‐exp