Tissue difference in gamma-glutamyl transpeptidase attributed to sialic acid content

Extra-cellular thiol metabolism in clone

Extra-cellular thiol metabolism in clones of human metastatic melanoma with different gamma-glutamyl transpeptidase expression: Implications for cell response to platinum-based drugs

✍ Aldo Paolicchi; Evelina Lorenzini; Paola Perego; Rosanna Supino; Franco Zunino; 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 114 KB

## Abstract Thiol redox status can affect important functions both intracellularly and extracellularly. The plasma membrane enzyme γ‐glutamyl transpeptidase (GGT), which plays a crucial role in cellular handling of thiols, is often expressed in malignant tumors, including melanoma, although its exp