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Tissue-dependent factors affect gene delivery to tumors in vivo

✍ Scribed by Smrekar, B; Wightman, L; Wolschek, M F; Lichtenberger, C; Ruzicka, R; Ogris, M; Rödl, W; Kursa, M; Wagner, E; Kircheis, R

Book ID: 110039267
Publisher: Nature Publishing Group
Year: 2003
Tongue: English
Weight: 345 KB
Volume: 10
Category: Article
ISSN: 0969-7128
DOI: 10.1038/sj.gt.3301965

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## Abstract ## Background We have previously shown that a novel synthetic peptide for ocular delivery (POD) can efficiently compact DNA and deliver it to cells __in vitro.__ This observation prompted us to develop use of POD as a nonviral vector __in vivo.__ ## Methods POD peptide was modified u