Tissue characterization and calcification potential of commercial bioprosthetic heart valves
β Scribed by Crystal M Cunanan; Christine M Cabiling; Tan T Dinh; ShihHwa Shen; Phihoa Tran-Hata; James H Rutledge III; Michael C Fishbein
- Book ID
- 117033427
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 172 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0003-4975
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## Abstract The use of glutaraldehydeβtreated biological tissue in heart valve substitutes is an important option in the treatment of heart valve disease. These devices have limited durability, in part, because of tissue calcification and subsequent tearing of the valve leaflets. Components thought
The durability of bioprosthetic heart valves (BHV) is severely limited by tissue deterioration, manifested as calcification and mechanical damage to the extracellular matrix. Extensive research on mineralization mechanisms has led to prevention strategies, but little work has been done on understand