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TIMP-1 Overexpression in Pancreatic Cancer Attenuates Tumor Growth, Decreases Implantation and Metastasis, and Inhibits Angiogenesis

✍ Scribed by Mark Bloomston; Alexis Shafii; Emmanuel E. Zervos; Alexander S. Rosemurgy

Book ID
115636550
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
649 KB
Volume
102
Category
Article
ISSN
0022-4804

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## Abstract The tissue inhibitor of matrix metalloproteinases‐1 (TIMP‐1) has been recognized as a multifunctional protein. The role of TIMPs in cancer remains the subject of conflicting reports with an antitumor activity or a tumor growth stimulation activity by several mechanisms. The aim of our s