Pharmacokinetics of timolol in aqueous h
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Gang Wei; Ping-Tian Ding; Jun-Min Zheng; Wei-Yue Lu
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Article
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2005
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John Wiley and Sons
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English
⚖ 103 KB
In order to develop a thermosetting gel-based formulation, the ocular pharmacokinetics of timolol was studied utilizing microdialysis sampling technique after topical administration. A linear microdialysis probe was characterized and implanted in the anterior chamber of a rabbit. Dialysate samples c