Time resolved analysis of tubulin phosphorylation during platelet activation
โ Scribed by Susan Berry; Doloretta D. Dawicki; Manfred Steiner
- Book ID
- 115762406
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 694 KB
- Volume
- 159
- Category
- Article
- ISSN
- 0006-291X
No coin nor oath required. For personal study only.
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In this study, we have used the tumor promoter 12-o-tetradecanoylphorbol-13acetate (TPA), as well as its biologically inactive analogue 4a-phorbol 12,13didecanoate (4cu-PDD), to investigate platelet protein phosphorylation and its possible correlation with platelet activation. Our data show that TPA
## Abstract ## Background and Objective Platelet activation during percutaneous transluminal coronary angioplasty (PTCA) initiates thrombus formation and plaque regrowth at sites of arterial injury, limiting procedure efficacy. We have developed a simple assay for circulating platelet activation b