Influence of culture time on the express
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Stefan Wilkening; Augustinus Bader
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Article
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2003
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John Wiley and Sons
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English
β 129 KB
π 1 views
## Abstract Primary cultures of human hepatocytes and hepatoma cell line HepG2 are frequently used to evaluate the hepatic disposition of drugs and other xenobiotics. To check the variability of the expression of drugβmetabolizing enzymes in these in vitro models, expression of genes coding for sev