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Time-dependent Pharmacokinetics of High Dose Thiopental Infusion in Intensive Care Patients

✍ Scribed by Hélène Russo; Marie P. Dubboin; Françoise Bressolle; Saïk Urien


Book ID
110309179
Publisher
Springer US
Year
1997
Tongue
English
Weight
457 KB
Volume
14
Category
Article
ISSN
0724-8741

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✍ H. Russo; J. Brès; M. P. Duboin; B. Roquefeuil 📂 Article 📅 1995 🏛 Springer 🌐 English ⚖ 967 KB

Thiopental was administered to neurosurgical patients for cerebral protection and its pharmacokinetic parameters were determined after a single bolus of 540, 1000 or 1500 mg (3 subjects) or after multiple doses of 250 mg (5 subjects) and 500 mg (2 subjects) every two hours for up to 7 days. The data