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Time-dependent changes in striatal glutamate synapses following a 6-hydroxydopamine lesion

✍ Scribed by C.K Meshul; N Emre; C.M Nakamura; C Allen; M.K Donohue; J.F Buckman


Book ID
117492480
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
262 KB
Volume
88
Category
Article
ISSN
0306-4522

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We reported previously that 3 months following a unilateral lesion of the nigrostriatal pathway with 6-hydroxydopamine (6-OHDA), there was a decrease in the extracellular level of striatal glutamate as determined by in vivo microdialysis. This resulted in an accumulation or increase in the density o